Study of canine genetics holds clues to better human health Mon, 27 Jun 2016 06:14:00 GMT Could dogs hold the key to better medical treatments for people? Elinor Karlsson, PhD, assistant professor of molecular medicine, is studying canine genetics to better understand human health. Dr. Karlsson uses evolution as a tool to learn how the human ... Read more
The canine connection Tue, 28 Jun 2016 00:41:00 GMT The dogs also are ambassadors and conversation starters for public wildlife education, "They have the genetics to do it all very well," said wildlife biologist Rich Beausoleil, the agency's bear-cougar specialist in Wenatchee. Most of the dogs were ... Read more
Genetic mutation causes ataxia in humans, dogs Thu, 16 Jun 2016 01:00:00 GMT Cerebellar ataxia is a condition of the cerebellum that causes an inability to coordinate muscle movements. A new study describes a new genetic mutation as an additional cause of ataxia in humans and mice. The mutation, in the gene CAPN1, affects the ... Read more
CSI: Canine crackdown Mon, 20 Jun 2016 22:54:00 GMT "Nothing was working," she says. "It just seemed to get worse." That's when a prospective tenant told Baty about PooPrints a dog DNA database and genetic service developed by BioPet, a canine research laboratory based in Knoxville, Ten Read more
Are We Any Better Than Yulin Dog Meat Festival-Goers? Sun, 26 Jun 2016 17:09:00 GMT While 10,000 dogs will meet a gruesome death during the Yulin Festival ... The chickens we raise for meat aren't locked in cages, but they are prisoners of their own genetics, which have been manipulated by the poultry industry for abnormally rapid growth. Read more
Genetics and the Social Behavior of Dogs A classic study gathered into one volume. Based on twenty years of research at the Jackson Laboratory, this is the single most important and comprehensive reference work.
Canine Genetics section of the Working Dogs Book Store features genetic studies and reference resources.
Note: The two resources immediately below are particularly helpful for reviewing the basics before ramping up to more advanced discussions about canine genetics:
Berkeley professors Melissa DeMille and C. Denise Wall present the Bare Bones Introduction to Genetics that introduces the major terms and concepts customarily used when discussing canine genetics.
In the Canine Genetic Primer, a cadre of genetics professionals collaborate to create an excellent resource for basic canine genetics on the Acmepet web site.
Canine Inherited Disorders Database intends to reduce the incidence of inherited disorders in dogs by providing information to owners and breeders, and to facilitate the best management possible of these conditions by providing current information to veterinarians. Featuring general information about inherited disorders and the breeds affected, particularly well done is their section "How Are Defects Inherited?". The site is under development with anticipated completion by 2001.
In their six-part series, authors Susan Thorpe-Vargas, John Cargill and Caroline Coile discuss how a single breeder's actions may have consequences that are far-reaching. Selective breeding practices may have created a genetic nightmare for many of our breeds today. In the first installment of that series, The Genetic Cul-de-Sac, the genetics task force addresses the origin of the domestic dog with an emphasis on the fundamentals of DNA and gene mutations, and their relationship to vigorous genetic diversity.
Prof. Sue Ann Bowling's Animal Color Genetics page features an excellent library of articles about population genetics, canine coat color genetics, inheritance, inbreeding, and much more.
UNE's GENUP software contains a number of learning modules. Each of these is designed to help you master concepts in Quantitative Genetics and its application to Animal Breeding.
"Heritability" is a statistic used to evaluate dogs and selectively breed them for a quantitative trait. Cornell geneticist John Pollack explains how Heritability Measures the Variability of Genes that can control physical characteristics.
The Canine Diversity web site features Genetic Testing: A Guide for Breeders by Mary Whiteley, PhD. Dr. Whiteley believes that we will soon have a test for most of the genetic diseases of dogs. In her article, she discusses genes, DNA, the genetic testing that is available to breeders today, and what the test results mean. Also on this site -- information about subscribing to the CANGEN email list for discussions about canine genetics and related topics.
Dealing effectively with any genetic problem requires an understanding of the relationship between the genes (genotype) and the phenotype. In his article, The Nature of Genetic Disease, Dr. John B. Armstrong sheds light on the differences between true genetic diseases and conformational diseases.
Online Mendelian Inheritance in Animals (OMIA) presented by the Dept. of Animal Science at the University of Sydney, Australia includes information about species, genetic maps, traits, and disorders,, such as inherited bleeding disorders, dwarfism, heart defects, and more.
Michigan University presents Laboratory of Molecular Medicine and Canine Genetics, "using the powerful new tools of molecular genetics to understand, improve diagnosis and treatment of, and ultimately prevent the hereditary diseases that affect dogs and (B) to educate and train veterinary professionals and scientists in molecular genetics and medicine."
The Dogs in Canada web site features Siberian Husky breeder Jeffrey Bragg's commentary on the upsurge of genetic problems and his call for action in The Genetic Tide: Will It Leave Us High and Dry? We are seeing a steady increase in genetic defects. Bragg suggests that the answer lies in the well-proven science of population genetics.
Fred Hutchinson Cancer Research Center's Current Canine Linkage Map of the canine genome with mapped markers, pedigrees, and resources.
The Dog Map is "an international collaboration between 46 labs from 20 different countries towards a low resolution canine marker map under the auspices of the International Society for Animal Genetics (ISAG)."
Dr. John B. Armstrong's Canine Diversity Project acquaints breeders of domesticated dogs with the dangers of inbreeding and the overuse of pre-eminent males.
The Control of Genetic Disease is discussed in a summary of information presented at seminars by Dr. George A. Padgett, DVM, a veterinary pathologist specializing in canine genetics.
The Open Disease Registry established by the Institute for Genetic Disease Control in Animals is the first open registry in the United States. Learn how the GDC helps the dog-owning public and responsible breeders identify and prevent genotypic and phenotypic disease.
Guide to Hereditary and Congenital Diseases in Dogs (Includes Genetic Predisposition to Diseases). Published by The Association of Veterinarians for Animal Rights. Includes a list of 148 purebred dog breeds with their genetic predisposition to diseases; plus an alphabetical listing and brief description of the genetically transmitted diseases.
Canadian Jeffrey Bragg details his arguments for achieving genetic soundness in his stimulating brief, Purebred Dog Breeds into the Twenty-First Century: Achieving Genetic Health for Our Dogs. Promoting a balanced, heterozygous breeding system, he focuses on the tremendous amount of work that is required of responsible breeders to preserve and advance canine working abilities. His model for genetic diversity demands a rational balance between working characteristics and the ideals of conformation.